Dr. Stacey Simmons, editorial director of Breakthrough Clinical writes this month’s oral pathology case. A 62-year-old female presents for her biannual cleaning and checkup. Health history is noncontributory; she is taking Vitamin D supplements and reports no other changes or concerns. During her routine oral screening and exam, a 9 mm x 3 mm white leukoplakic patch of tissue on the left ventral surface of the tongue was noted. It was not tender to palpation, could not be scraped off, and the patient was unaware of its presence. At the follow-up appointment two-and-a-half weeks later, the lesion was still present.